ASK NINA: APPA BROWN EYES
By: JJosepha News
Twitter.com/JJosephaNews
Dear Nina:
Hi, I read your tweet about DNA testing and wanted to ask you a question.
My wife and I have a good relationship and have been married for a few years now.
We just recently had our first child, and she is the most precious thing I have ever seen.
However; I am concerned a little because she is growing older and has blond hair and blue eyes, but I am a light skin Indian with dark brown eyes and black hair and so are my appa and amma.
My wife has brown coloured eyes and hair as well, but she is a Caucasian Curacao girl with Spanish and Portuguese ancestry.
I have heard stories where sometimes hospital workers have mismatched and crossed children, giving parents the wrong baby, but my wife tells to me that she will never give back our baby, no matter what!
My mother-in-law says that the child has all of her genes and that explains why the child has white skin, blue eyes and blondish hair colour. But my wife’s sisters all have brown eyes and hair colour.
I thought about taking the DNA test but my wife says that it is real expensive.
Can you help answer me about the hospital and DNA testing?
Sincerely,
Appa Brown Eyes
Appa Brown Eyes
Dear Appa Brown Eyes,
First of all congratulations on your first born and your marriage.
1. Resolving your immediate concern about DNA testing
a) In Curacao there is a DNA testing centre, called Curacao DNA Collection Center BV. They offer a full range of DNA genetic services that includes paternity (prenatal) DNA testing, maternity DNA testing, family relationship DNA tests, identity DNA tests and immigration DNA testing. You can contact them about an appointment, testing and the cost involved.
b) In addition; there are also a do-it-yourself DNA testing kits, sold in some pharmacies and the directions are straightforward. (This is least expensive.)
c) Lastly, if you would like you can leave me a message on Twitter and I can contact the director directly of the USA Genetic Diagnostic Center for you and put you in contact with them directly.
2. About baby switching in the hospital In real life, such a switch occurs rarely. Since many cases of babies switched at birth are likely undocumented or unknown and especially since there are anti-switch techniques implemented globally as well as in Curacao’s Hospital.
You may have a better chance of winning the Florida Lottery on Curacao than having your baby switched in the hospital. I am saying that the possibility of that occurring is extremely rare but not impossible. 3. Basic genetics and heredity What you may need to know is that there are dominant genes and recessive genes. The physical expression of the genetic trait is referred to as the phenotypical expression, and the genotypical expression is the genetic composition of the pair in the hereditary express trait.
Eye colour, skin colour and hair colour are genetic expression of dominance hereditary. Eye colour is a genetic expression and in genetic and hereditary, there can be the following expressions: 1. Complete Dominance, 2. Incomplete Dominance and 3. Partial Dominance. Let’s say brown is dominant [B] and Blue is recessive (b). This means that whenever [B] is present in the pair, it will be expressed over the other gene in this case (b). To keep it simple these "genes" always occur in pairs of either of the four: BB or Bb or bB or bb . Whenever it is, two of the same kind genotypically it is called Homozygous and, whenever it is not 2 of the same kind in a pair, genotypically it is called Heterozygous. (0A) So you can figure out that your mother-in-law is of the type Homozygous Recessive (b)(b) and that’s why she has the phenotypical expression of blue eye colour Now if your father-in-law had blue eyes also then he would more than likely be of the genotypical expression (b)(b) but that would mean all of this daughters would be blue eyes and they are not because you said your wife’s eyes are brown. Therefore; your father-in-law had to have been either: (1A) Homozygous Brown eye colour with a genotypical expression of [B][B] or, (1B) Heterozygous Brown eye colour with a genotypical expression of [B](b). Now, that means that your wife could only be Heterozygous Brown eye colour with a genotypical expression of [B](b), because one gene would have come from her mother (b) and the other from her father in 1A = [B] or in 1B = [B]. It would not be (b) that would have come from her father because then that would have made your wife (b)(b) and therefore blue eyes. Now, therefore; if you have anyone in your family that would have coloured eyes or blue eyes in your Indian ancestry there is a chance that you may be carrying a recessive (b) gene in your genome. However; you don’t have any direct family ancestry with that trait (you stated that both your parents have brown eye colour), then chances are more than likely that you do not have the blue eye gene trait (b) and therefore it is virtually impossible for you to have fathered a blue eye child under complete dominance inheritance. Sorry to be the bearer of bad news if this is the case! Therefore, what may be happening: (2A) you are Probably [B][B] and your wife is [B](b) Therefore, the only genotypical expression of any of your possible children; possible in accordance to complete dominance inheritance can only be: (3A1) [B][B] : [B](b) : [B][B] : [B](b) or, (3A1-1) in ratios: 2[B][B] : 2[B](b) or, (3A1-2) in terms of percentages: (3A-2.1) There is a 50% chance of you having a genotypical – homozygous dominant [B][B] child that’s phenotypically a brown coloured eye child, or (3A-2.2) There is a 50% chance of you having a genotypical – heterozygous dominant [B][b] child that’s phenotypically a brown coloured eye child. In the rare event that someone in your direct ancestry (for example, your mother; father or grandparents or that they are heterozygous brown eye) has blue eyes then there exist a 25% chance of a phenotypical blue eye child and, (3B-1.1) the possibility of a genotypical ratio expression of: 1 homozygous {brown eye} [B][B] : 2 heterozygous {brown eye} [B](b) :1 homozygous {blue eye} (b)(b) or (3B-1.2) the possibility of a genotypical ratio expression of: 25% homozygous {brown eye} [B][B] : 50% heterozygous {brown eye} [B](b) : 25% homozygous {blue eye} (b)(b) and; (3B-1.2.1) the phenotypical expression of: 75% brown eye: 25% blue eye. I wish you the best in all your efforts and hope I have been of some help and assistance to you understanding your situation much better and much more. Thank you for contacting me and sharing your situation with us at Ask Nina! I hope that this has been I hope that this has been educational and informative for both you and our readers.
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About Ask Nina
"Ask Nina" is an advice column founded, created and operated by Josefina Josepha under the pen name of "Nina". The advice column is managed by JJosepha News. The advice column’s mission is to impart compassionate, sound advice and incorporating expert advice sought from authorities, while delivering a layman’s approach with the straightforward style of a good friend. Have a question, need an answer, Ask Nina!
DISCLAIMER: The advice offered in this column is intended for informational purposes only. The use of this column is not intended to replace or substitute for any professional, financial, medical, legal, or other professional advice. If you have specific concerns or a situation in which you require professional, psychological or medical help, you should consult with an appropriately trained and qualified specialist. The opinions or views expressed in this column are not intended to treat or diagnose; nor are they meant to replace the treatment and care that you may be receiving from a licensed professional, physician or mental health professional. This column, its author, the newspaper and publisher are not responsible for the outcome or results of following any advice in any given situation. You, and only you, are completely responsible for your actions.
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